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The EpiPen, manufactured by Meridian Medical Technologies, and marketed by Mylan, has dominated the market. [57] In 2007 when Mylan acquired the rights to market the product, annual sales of all epinephrine autoinjectors were about $200 million and EpiPen had around 90% of the market; in 2015 the market size was around $1.5 billion and Mylan ...
[14] [15] Epinephrine does this through its effects on alpha and beta receptors. [15] It is found in many animals and some single-celled organisms, [16] [17] but the medication is produced synthetically and is not harvested from animals. [18] Jōkichi Takamine first isolated epinephrine in 1901, and it came into medical use in 1905.
A military autoinjector in use. An autoinjector (or auto-injector) is a medical device for injection of a premeasured dose of a particular drug.Most autoinjectors are one-use, disposable, spring-loaded syringes (prefilled syringes).
The FDA just approved Neffy, a needle-free EpiPen alternative. Here's when it's hitting shelves—and allergists tell 'Women's Health' if they recommend it.
The spray, which will be sold under the brand name neffy, is seen as an alternative to EpiPen and other autoinjectors that are filled with epinephrine, a life-saving drug used by people at risk of ...
Adrenaline does not readily cross the blood-brain barrier, so its effects on memory consolidation are at least partly initiated by β adrenoceptors in the periphery. Studies have found that sotalol , a β adrenoceptor antagonist that also does not readily enter the brain, blocks the enhancing effects of peripherally administered adrenaline on ...
Christopher Wren performed the earliest confirmed experiments with crude hypodermic needles, performing intravenous injection into dogs in 1656. [7] These experiments consisted of using animal bladders (as the syringe) and goose quills (as the needle) to administer drugs such as opium intravenously to dogs. Wren and others' main interest was to ...
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