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A medical isotope is an isotope used in medicine. The first uses of isotopes in medicine were in radiopharmaceuticals , and this is still the most common use. However more recently, separated stable isotopes have come into use.
Some radioisotopes (for example gallium-67, gallium-68, ... and tend to be most easily produced using a proton accelerator such as a medical cyclotron. ...
Technetium-99m was discovered as a product of cyclotron bombardment of molybdenum. This procedure produced molybdenum-99, a radionuclide with a longer half-life (2.75 days), which decays to 99m Tc. This longer decay time allows for 99 Mo to be shipped to medical facilities, where 99m Tc is extracted from
Lawrence's 60-inch (152 cm) cyclotron, c. 1939, showing the beam of accelerated ions (likely protons or deuterons) exiting the machine and ionizing the surrounding air causing a blue glow. A cyclotron is a type of particle accelerator invented by Ernest Lawrence in 1929–1930 at the University of California, Berkeley, [1] [2] and patented in 1932.
While 99m Tc is extracted from relatively simple technetium-99m generators, which are delivered to hospitals and scanning centers weekly to supply fresh radioisotope, FDG PET relies on FDG, which is made in an expensive medical cyclotron and "hot-lab" (automated chemistry lab for radiopharmaceutical manufacture), and then delivered immediately ...
Radioisotopes can occur naturally or be synthesized and produced in a cyclotron/nuclear reactor. The different types of radioisotopes include Y-90, H-3, C-11, Lu-177, Ac-225, Ra-223, In-111, I-131, I-125, etc. Thus, radioligands must be produced in special nuclear reactors for the radioisotope to remain stable. [1]
Some radioisotopes are used in ionic or inert form without attachment to a pharmaceutical; these are also included. There is a section for each radioisotope with a table of radiopharmaceuticals using that radioisotope. The sections are ordered alphabetically by the English name of the radioisotope.
This page lists radioactive nuclides by their half-life.