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Fannyhessea vaginae is a species of bacteria in the family Atopobiaceae. It is a facultative anaerobic, Gram-positive rod-shaped or elliptical coccobacillus found as single elements or in pairs or short chains. [2] It is typically isolated from 80% of women with bacterial vaginosis and it is implicated in treatment failures.
Structurally it actually methyl-metronidazole. Effectiveness in the treatment of dientamoebiasis has been reported. [1] It has also been tested against Atopobium vaginae. [2] In the United States, secnidazole is FDA approved for the treatment of bacterial vaginosis and trichomoniasis in adult women. [3]
Atopobium species are anaerobic, Gram-positive rod-shaped or elliptical bacteria found as single elements or in pairs or short chains. Atopobium vaginae was discovered in 1999. [ 2 ] This is a facultative anaerobic bacteria, which form small colonies on blood agar at 37 °C is also positive for acid phosphatase.
Treatment include antibiotics, specifically metronidazole and clindamycin (Hay, 2010). Studies have shown a correlation between vaginal microbiota and BV development through 16S RNA sequencing. Community state types (CSTs) are used to identify variation between a healthy vaginal microbiota and vaginal microbiota of someone with BV.
A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy.Kjersti Aagaard, Kevin Riehle, Jun Ma, Nicola Segata, Toni-Ann Mistretta, Cristian Coarfa, Sabeen Raza, Sean Rosenbaum, Ignatia Van den Veyver, Aleksandar Milosavljevic, Dirk Gevers, Curtis Huttenhower, Joseph Petrosino, James Versalovic.
Atopobium, Olsenella, and Cryptobacterium species have responsible for human oral infections including periodontitis, halitosis, and other endodontic infections. [ 9 ] [ 10 ] Eggerthella species have been associated with severe blood bacteraemia and ulcerative colitis .
Gram stain of cells from the vagina (the same magnification) with normal bacterial flora (top) and the bacteria that cause vaginosis (bottom). A variety of diagnosis techniques are currently available for identifying Gardnerella vaginalis such as the OSOM BV Blue assay, FemExam cards and nucleic acid amplification tests (NAATs), resulting in the determination of ongoing BV.
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