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The alkaloid mixture or its sulphated form mixed in alcohol and sold as quinetum was however very bitter and caused nausea, among other side effects. [52] Cinchona alkaloids include: cinchonine and cinchonidine (stereoisomers with R 1 = vinyl, R 2 = hydrogen) quinine and quinidine (stereoisomers with R 1 = vinyl, R 2 = methoxy)
Cinchonism is a pathological condition caused by an overdose of quinine or its natural source, cinchona bark. Quinine and its derivatives are used medically to treat malaria and lupus erythematosus. In much smaller amounts, quinine is an ingredient of tonic drinks, acting as a bittering agent. Cinchonism can occur from therapeutic doses of ...
Adverse effects Cinchona bark Cinchona pubescens: Warfarin Possible additive effect [3] Chamomile: Blood thinners [23] Devil's Claw: grapple plant, wood spider Harpagophytum: Warfarin Additive effect [3] Ephedra Ephedra: Caffeine, decongestants, stimulants [15] Increases sympathomimetic effect of ephedra [3] Feverfew: featherfew Tanacetum ...
Cinchona officinalis is a shrub or tree with rugose bark and branchlets covered in minute hairs. Stipules lanceolate or oblong, acute or obtuse, glabrous. Leaves lanceolate to elliptic or ovate, usually about 10 centimetres (3.9 in). long and 3.5–4 centimetres (1.4–1.6 in). wide; acute, acuminate, or obtuse tip; base rounded to attenuate; coriaceous, glabrous above and often lustrous ...
The US had obtained four million cinchona seeds from the Philippines and began operating cinchona plantations in Costa Rica. Additionally, they began harvesting wild cinchona bark during the Cinchona Missions. Such supplies came too late. Tens of thousands of US troops in Africa and the South Pacific died of malaria due to the lack of quinine. [64]
Jesuit's bark, also known as cinchona bark, Peruvian bark or China bark, is a former remedy for malaria, as the bark contains quinine used to treat the disease. [1] The bark of several species of the genus Cinchona , family Rubiaceae indigenous to the western Andes of South America, was introduced to Jesuit missionaries during the 17th century ...
Cinchona pubescens, also known as red cinchona and quina or kina (Spanish: Cascarilla, cinchona; Portuguese: quina-do-amazonas, quineira), is native to Central and South America. It is known as a medicinal plant for its bark's high quinine content- and has similar uses to C. officinalis in the production of quinine, most famously used for ...
Cinchonine is an alkaloid found in Cinchona officinalis.It is used in asymmetric synthesis in organic chemistry. It is a stereoisomer and pseudo-enantiomer of cinchonidine.It is structurally similar to quinine, an antimalarial drug.