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Serum sickness in humans is a reaction to proteins in antiserum derived from a non-human animal source, occurring 5–10 days after exposure. Symptoms often include a rash , joint pain , fever , and lymphadenopathy .
While optimal treatment strategies for serum sickness–like reactions are not clearly defined in the literature, discontinuation of the suspected agent combined with use of antihistamines, corticosteroids and NSAIDs for symptom control is an appropriate therapeutic route.
[2]: 118 As of 2015, two cases of AHS have been reported that manifested during long-term treatment with multiple anti-seizure medications. Death due to multiple organ failure can occur; symptoms also mimic lymphoma and AHS has been called "pseudolymphoma" as a result. Changing the medications involved to those in a different class can avoid ...
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
Later during the treatment, some patients develop serum sickness or immune complex glomerulonephritis. Serum sickness arises seven to fourteen days after the therapy has begun. The patient has fever, joint pain, and erythema that can be soothed with the use of steroids and analgesics. Urticaria (hives) can also be present.
Dimenhydrinate, also known by the brand name Dramamine, is a popular option to help reduce motion sickness symptoms like nausea. However, it is an antihistamine, which means it may cause ...
This mechanism is seen in serum sickness and is associated with systemic symptoms such as fever, joint pain, and neurological symptoms. [4] Some medications, like opioids and certain other drugs, induce urticaria by directly acting on mast cells, triggering histamine release. [2] Non-steroidal anti-inflammatory drugs (NSAIDs) contribute ...
Sanofi's Fexinidazole Winthrop is the first oral treatment for an acute form of sleeping sickness, a lethal parasitic disease transmitted by the bite of infected tsetse flies and found in 36 ...
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