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Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]
Unlike supplemental calcium, high intakes of dietary calcium do not appear to cause kidney stones and may actually protect against their development. [30] [29] This is perhaps related to the role of calcium in binding ingested oxalate in the gastrointestinal tract. As the amount of calcium intake decreases, the amount of oxalate available for ...
Thiazides may be used to treat the symptoms of Dent's disease, an X-linked genetic condition that results in electrolyte imbalance with repeated episodes of kidney stones. A case study of two brothers with the condition, two years of treatment with hydrochlorothiazide reduced the incidence of kidney stones and improved kidney function. [22]
Three different tests may be used to measure calcium levels in urine, 24-hour urine tests, blood tests, and genetic tests. Measuring calcium levels can also be done using an oral calcium tolerance test. [24] Ultrasound and CT scans of the urinary tract can be done to diagnose kidney stones or kidney abnormalities as IH often accompanies it.
Other causes of hypercalcemia include sarcoidosis, tuberculosis, Paget disease, multiple endocrine neoplasia (MEN), vitamin D toxicity, familial hypocalciuric hypercalcaemia and certain medications such as lithium and hydrochlorothiazide.
Many stone types can be detected by ultrasound; Factors contributing to stone formation (as in #Etiology) are often tested: Laboratory testing can give levels of relevant substances in blood or urine; Some stones can be directly recovered (at surgery, or when they leave the body spontaneously) and sent to a laboratory for analysis of content
Myth #7: Nuts lead to kidney stones. Nuts are oftentimes said to cause kidney stones as they can be high in oxalates. Oxalates are compounds that can bind with minerals like calcium, potentially ...
Triamterene is commonly prepared in combination with hydrochlorothiazide for treatment of hypertension (high blood pressure) and edema (water retention). This combination is in a class of medications called diuretics or 'water pills', and causes the kidneys to get rid of the body's unneeded water and sodium through the urine. [6]
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