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Brain anatomy – forebrain, midbrain, hindbrain. The cerebral peduncles each form a lobe ventrally of the tegmentum, on either side of the midline. Beyond the midbrain, between the lobes, is the interpeduncular fossa, which is a cistern filled with cerebrospinal fluid [citation needed]. The majority of each lobe constitutes the cerebral crus.
The brainstem, resembling a stalk, attaches to and leaves the cerebrum at the start of the midbrain area. The brainstem includes the midbrain, the pons, and the medulla oblongata. Behind the brainstem is the cerebellum (Latin: little brain). [7] The cerebrum, brainstem, cerebellum, and spinal cord are covered by three membranes called meninges.
Cross-section of the midbrain. Tectum. Corpora quadrigemina. Inferior colliculi; Superior colliculi; Pretectum; Tegmentum. Periaqueductal gray; Rostral interstitial nucleus of medial longitudinal fasciculus; Midbrain reticular formation; Dorsal raphe nucleus; Red nucleus; Ventral tegmental area. Parabrachial pigmented nucleus; Paranigral ...
Anatomically, as the name suggests, the MLR is located in the mesencephalon (or midbrain), ventral to the inferior colliculus and near the cuneiform nucleus. [6] Although identifying the exact anatomical substrates of the MLR has been subject to considerable debate, the pedunculopontine nucleus (PPN), cuneiform nucleus, and midbrain ...
The cerebral peduncles (In Latin, ped-means 'foot'.) are the two stalks that attach the cerebrum to the brainstem. [1] They are structures at the front of the midbrain which arise from the ventral pons and contain the large ascending (sensory) and descending (motor) tracts that run to and from the cerebrum from the pons.
The mesolimbic pathway transmits dopamine from the ventral tegmental area (VTA), which is located in the midbrain, to the ventral striatum, which includes both the nucleus accumbens and olfactory tubercle. [5] [6] The "meso" prefix in the word "mesolimbic" refers to the midbrain, or "middle brain", since "meso" means "middle" in Greek.
Neuroanatomists usually divide the vertebrate brain into six main subregions: the telencephalon (the cerebral hemispheres), diencephalon (thalamus and hypothalamus), mesencephalon (midbrain), cerebellum, pons and medulla oblongata, with the midbrain, pons and medulla often collectively called the brainstem. Each of these areas has a complex ...
Stimulation of the periaqueductal gray matter of the midbrain activates enkephalin-releasing neurons that project to the raphe nuclei in the brainstem. 5-HT released from the raphe nuclei descends to the dorsal horn of the spinal cord where it forms excitatory connections with the inhibitory interneurons located in Laminae II (aka the substantia gelatinosa).