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Eosinophilic esophagitis (EoE) is an allergic inflammatory condition of the esophagus that involves eosinophils, a type of white blood cell. In healthy individuals, the esophagus is typically devoid of eosinophils. [ 2 ]
Eosinophilic esophagitis, an immune system reaction to certain foods, allergens or environmental factors, can cause damage to the esophageal lining, leading to swelling, scarring and narrowing of ...
Eosinophilic esophagitis The presence of eosinophils in the esophagus may be due to an allergen and is often correlated with GERD. The direction of cause and effect between inflammation and acid reflux is poorly established, with recent studies (in 2016) hinting that reflux does not cause inflammation. [ 6 ]
The endoscopic appearance in eosinophilic gastroenteritis is nonspecific; it includes erythematous, friable, nodular, and occasional ulcerative changes. [21] Sometimes diffuse inflammation results in complete loss of villi, involvement of multiple layers, submucosal oedema and fibrosis. [22] [23]
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The signs and symptoms of hypereosinophilia may include weight loss, night sweats, asthma, cough, abdominal pain, and gastrointestinal bleeding. [7] Fever and malaise are often present. [14] The eosinophilic stage can last months or years, and its symptoms can disappear, only to return later. [7]
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