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The cause is unknown, but it may result from an initial viral infection or cancer, either of which could raise an autoimmune response. [12] Between 7 and 30% of dermatomyositis cases arise from cancer, probably as an autoimmune response. [13] The most commonly associated cancers are ovarian cancer, breast cancer, and lung cancer. [13]
One of the most common types of drugs that can cause myositis are statins, which are used to lower cholesterol levels. One of the most common side effects of statin therapy is muscle pain [5] which, more rarely, can lead to myositis. [5] Infection - The most common infectious cause of myositis is viral infections, such as the common cold. [4]
Juvenile dermatomyositis (JDM) is an idiopathic inflammatory myopathy (IMM) of presumed autoimmune dysfunction resulting in muscle weakness among other complications. It manifests itself in children; it is the pediatric counterpart of dermatomyositis .
It can also be associated with underlying cancer. The main classes of idiopathic inflammatory myopathy are polymyositis (PM), dermatomyositis (DM) (including juvenile, amyopathic, and sine-dermatitis form), inclusion-body myositis (IBM), immune-mediated necrotising myopathy (IMNM), and focal autoimmune myositis.
Melasma affects up to 33 percent of men and women. Read on to learn what causes the chronic skin condition and what you can do to keep it at bay.
The long-term course of MCTD may vary. Long-term follow-up studies have shown that MCTD can progress to a moderate disease with a favorable prognosis, or patients can acquire a significant condition with vascular alterations driven by pulmonary hypertension and increased mortality. Approximately one-third of people with MCTD have a benign ...
A former Playboy model killed herself and her 7-year-old son after jumping from a hotel in Midtown New York City on Friday morning. The New York Post reports that 47-year-old Stephanie Adams ...
Diagnosis of many conditions often also requires a skin biopsy which yields histologic information [22] [23] that can be correlated with the clinical presentation and any laboratory data. [24] [25] [26]