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Other effects of PCBs in animals include changes in the immune system, behavioral alterations, and impaired reproduction. [55] PCBs that have dioxin-like activity are known to cause a variety of teratogenic effects in animals. Exposure to PCBs causes hearing loss and symptoms similar to hypothyroidism in rats. [70]
Because current human evidence is incomplete, there is only data suggesting the carcinogenic effects of PCBs in humans. [15] While little research has been done on the toxic effects of 2,2’,3,3’,4,4’-hexachlorobiphenyl, PCBs have been found to cause irritation in the eyes and when inhaled also in the airways.
PCB contamination in humans may come from drinking the contaminated water, absorption through the skin, eating contaminated aquatic life, and/or inhaling volatilized PCBs. PCB contamination is especially dangerous for pregnant and nursing women. The contamination can reach the fetus and potentially cause birth defects.
The PCB oil leaked to rice bran oil consumed by thousands of people in Japan (Yusho disease 1968) and Taiwan (Yu-cheng disease 1979). The toxic effects have been attributed to dioxin-like PCBs and PCDFs. Their daily intake was up to 100,000 times higher than average intake presently. [1]
Ortho-PCBs may alter hormone regulation through disruption of the thyroid hormone transport by binding to transthyretin. [8] Coplanar PCBs are similar to dioxins and furans, both bind to the aryl hydrocarbon receptor (AhR) in organisms and may exert dioxin-like effects, in addition to the effects shared with non-coplanar PCBs.
(Reuters) -A Washington jury on Tuesday ordered Bayer to pay $100 million to four people who say they were sickened by toxic chemicals known as PCBs at a Seattle-area school, but found the company ...
Numerous chemicals from the site, including benzene, PCBs, toluene and more, resulted in side effects of irritated eyes, vomiting, diarrhea and skin rashes. The long term effects from the exposure of the chemicals can be seen in firefighters who have developed lung diseases, cancer, blood disorders, and nerve damage. [6]
Test results conducted in the fall showed the presence of PCBs, or polychlorinated biphenyls — toxic, man-made chemicals that were banned from being produced in the United States in 1979.
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