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Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine. RCC is the most common type of kidney cancer in adults, responsible for approximately 90–95% of cases. [ 1 ]
Renal oncocytoma is considered benign, cured by nephrectomy. There are some familial cases in which these tumors are multicentric rather than solitary. [4] However, they may be resected to exclude a malignant tumor, e.g. renal cell carcinoma.
The most frequent, malignant, primary kidney cancer is renal cell carcinoma (RCC) - which has several subtypes: Clear cell RCC, an epithelial cell tumour of the kidney that accounts for 65-70% of all RCCs. [5] Papillary RCC, a renal tumour that accounts for 10-15% of all RCCs. Males are 1.5 times as likely to develop this type of tumour than ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 18 January 2025. Medical condition Kidney cancer Other names Renal cancer Micrograph showing the most common type of kidney cancer (clear cell renal cell carcinoma). H&E stain. Specialty Oncology nephrology Urology Symptoms Blood in the urine, lump in the abdomen, back pain Usual onset After the age of ...
Hybrid oncocytoma/chromophobe renal cell carcinoma is rare subtype of renal cell carcinoma. [1] It arises from intercalated cells of cortical collecting ducts of the kidney. It is associated with extreme hypodiploidy with multiple losses of entire chromosomes 1, 2, 6, 10, 13, 17, 21 and Y. [ citation needed ]
Hybrid oncocytoma/chromophobe carcinoma, found in 50% of cases, [8] is the most commonly found cancer, followed by chromophobe renal carcinoma, clear cell renal carcinoma, renal oncocytoma, and papillary renal cell carcinoma. [5] [8] People over 40 years old and men are more likely to develop kidney tumors, which are diagnosed at a median age ...
An oncocytoma is a tumor made up of oncocytes, epithelial cells characterized by an excessive amount of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. [ 1 ] [ 2 ] The cells and the tumor that they compose are often benign but sometimes may be premalignant or malignant .
Collecting duct carcinoma (CDC) is a type of kidney cancer that originates in the papillary duct of the kidney. It is rare, accounting for 1-3% of all kidney cancers. [ 2 ] It is also recently described; a 2002 review found just 40 case reports worldwide. [ 3 ]