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As per Falkow's original descriptions, the three postulates are: [1] "The phenotype or property under investigation should be associated with pathogenic members of a genus or pathogenic strains of a species. Specific inactivation of the gene(s) associated with the suspected virulence trait should lead to a measurable loss in pathogenicity or ...
Falkow is known as the father of the field of molecular microbial pathogenesis. [1] He formulated molecular Koch's postulates, which have guided the study of the microbial determinants of infectious diseases since the late 1980s. [2] Falkow spent over 50 years uncovering molecular mechanisms of how bacteria cause disease and how to disarm them. [1]
Koch's postulates (/ k ɒ x / KOKH) [2] are four criteria designed to establish a causal relationship between a microbe and a disease. The postulates were formulated by Robert Koch and Friedrich Loeffler in 1884, based on earlier concepts described by Jakob Henle, and the statements were refined and published by Koch in 1890. [3]
Microbial pathogenesis is a field of microbiology that started at least as early as 1988, with the identification of the triune Falkow's criteria, aka molecular Koch's postulates.
Smith v. Kansas City Title & Trust Co., 255 U.S. 180 (1921), was a United States Supreme Court case that helped define the range and scope of federal question jurisdiction in state corporate law matters. [1] The case dealt with whether or not a district court had the power to uphold the constitutional validity of the Federal Farm Loan Act of 1916.
Ocampo v. United States: 234 U.S. 91 (1914) sometimes considered one of the Insular Cases: Shreveport Rate Case: 234 U.S. 342 (1914) Commerce clause, regulation of intrastate railroad rates Coppage v. Kansas: 236 U.S. 1 (1915) Economic due process and yellow-dog contracts: Burdick v. United States: 236 U.S. 79 (1915) Legal effect of a pardon ...
Hardin v. Kentucky Util. Co., 390 U.S. 1 (1968) Schneider v. Smith, 390 U.S. 17 (1968) Epton v. New York, 390 U.S. 29 (1968) (per curiam) Knight v. Board of Regents, 390 U.S. 36 (1968) (per curiam) Paulaitis v. Paulaitis, 390 U.S. 36 (1968) (per curiam) Wetter v. City of Indianapolis, 390 U.S. 37 (1968) (per curiam) Bogart v. State Bar, 390 U.S ...
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