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  2. Signs and symptoms of Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms_of...

    Parkinson's disease patient showing a typical flexed walking posture in advanced stage. Signs and symptoms of Parkinson's disease are varied. Parkinson's disease affects movement, producing motor symptoms. [1] Non-motor symptoms, which include dysautonomia, cognitive and neurobehavioral problems, and sensory and sleep difficulties, are also ...

  3. Gangrene - Wikipedia

    en.wikipedia.org/wiki/Gangrene

    Gangrene toes in a diabetic. Gangrene is a type of tissue death caused by a lack of blood supply. [4] The feet and hands are most commonly affected. [1] If the gangrene is caused by an infectious agent, it may present with a fever or sepsis. [1] Symptoms may include: [1] a change in skin color to red or black; numbness; swelling; pain; skin ...

  4. Diabetic foot infection - Wikipedia

    en.wikipedia.org/wiki/Diabetic_foot_infection

    Diabetic foot infection is any infection of the foot in a diabetic person. [2] The most frequent cause of hospitalization for diabetic patients is due to foot infections. [ 3 ] Symptoms may include pus from a wound, redness, swelling, pain, warmth, tachycardia , or tachypnea. [ 4 ]

  5. Parkinson's disease - Wikipedia

    en.wikipedia.org/wiki/Parkinson's_disease

    The four cardinal motor symptoms of Parkinson's—bradykinesia (slowed movements), postural instability, rigidity, and tremor—are called parkinsonism. [9] [10] These four symptoms are not exclusive to Parkinson's and can occur in many other conditions, [11] [12] including HIV infection and recreational drug use.

  6. Diabetic foot ulcer - Wikipedia

    en.wikipedia.org/wiki/Diabetic_foot_ulcer

    Diabetic foot ulcer is a breakdown of the skin and sometimes deeper tissues of the foot that leads to sore formation. It is thought to occur due to abnormal pressure or mechanical stress chronically applied to the foot, usually with concomitant predisposing conditions such as peripheral sensory neuropathy, peripheral motor neuropathy, autonomic neuropathy or peripheral arterial disease. [1]

  7. Parkinsonism - Wikipedia

    en.wikipedia.org/wiki/Parkinsonism

    Parkinsonism is a clinical syndrome characterized by the four motor symptoms found in Parkinson's disease: tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1] [2] Parkinsonism gait problems can lead to falls and serious physical injuries. Other common symptoms include:

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  9. Parkinson's disease and gut-brain axis - Wikipedia

    en.wikipedia.org/wiki/Parkinson's_Disease_and_Gut...

    [10] [11] [4] [6] [12] In early stages of PD, non-motor symptoms occur prior to the onset of motor symptoms, contributing to a delay in PD diagnosis and even misdiagnosis in up to 15% of cases. [5] [6] By the time motor symptoms appear and treatment is initiated, there is already over 50% dopaminergic neuronal cell loss in the substantia nigra.

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