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Adenocarcinoma of the lung is the most common type of lung cancer, and like other forms of lung cancer, it is characterized by distinct cellular and molecular features. [1] It is classified as one of several non-small cell lung cancers (NSCLC), to distinguish it from small cell lung cancer which has a different behavior and prognosis.
Nearly 40% of lung cancers are adenocarcinomas, which usually originates in peripheral lung tissue. [10] Most cases of adenocarcinoma are associated with smoking; however, among people who have smoked fewer than 100 cigarettes in their lifetimes ("never-smokers"), [11] adenocarcinoma is the most common form of lung cancer. [12]
Acinar adenocarcinoma of the lung is a highly lethal disease. Overall, the five-year survival rates approximate 16% to 22%. Generally, survival is better in all stages for patients with the acinar (or papillary) pattern than it is in patients with the solid pattern, but considerably worse than those with the bronchioloalveolar pattern.
“About 50% of nonsmoker Asians [with lung cancer] ... They tend to develop in younger people and often have certain gene changes that are different from those in tumors found in people who smoke ...
Lung cancer is the most diagnosed and deadliest cancer worldwide, with 2.2 million cases in 2020 resulting in 1.8 million deaths. [3] Lung cancer is rare in those younger than 40; the average age at diagnosis is 70 years, and the average age at death 72. [2] Incidence and outcomes vary widely across the world, depending on patterns of tobacco use.
Adenocarcinoma in situ (AIS) of the lung —previously included in the category of "bronchioloalveolar carcinoma" (BAC)—is a subtype of lung adenocarcinoma.It tends to arise in the distal bronchioles or alveoli and is defined by a non-invasive growth pattern.
Lung tumor; A chest X-ray showing a tumor in the lung (marked by arrow) ... Primary tumors of the lung/pulmonary system: Bronchial leiomyoma, a rare, benign tumor;
This particular variant of lung cancer is usually asymptomatic and is found after chest x-rays are taken for other reasons. [7] Hemoptysis is seen occasionally [7] and, in some cases, distal obstruction of bronchi by blood clots or mucus plugs produces cough and/or infection. [1] Lesions often enlarge and progress slowly, over many years. [8]
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