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Spilanthol (affinin) is a fatty acid amide isolated from Acmella oleracea. [1] It is believed to be responsible for the local anesthetic properties of the plant. [2]Spilanthol permeates the human skin [3] and the inside lining of the cheeks in the mouth (buccal mucosa), [4] resulting in local as well as systemic pharmacological concentrations.
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Acmella is a genus of plants in the family Asteraceae, [3] [4] described as a genus in 1807. [5] [2] It is native to the Americas and has been introduced to Asia, Africa, the Pacific islands, and Australia.
Common names include brede mafane, spilanthes, tingflower, toothache plant, electric daisy, and buzz buttons. The flowers and leaves contain spilanthol , a local anesthetic . [ 1 ] [ 2 ]
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Acmella oleracea is a species of flowering herb in the family Asteraceae.Common names include toothache plant, Szechuan buttons, [2] paracress, jambu, [3] buzz buttons, [4] tingflowers and electric daisy. [5]
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