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Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1]
Osmotic release systems have a number of major advantages over other controlled-release mechanisms. They are significantly less affected by factors such as pH, food intake, GI motility, and differing intestinal environments. Using an osmotic pump to deliver drugs has additional inherent advantages regarding control over drug delivery rates.
The technique has been used and found particularly valuable in a developing country with little access to dental services, or resources to support such services. [8] It is also utilized in modern dental practices, as many parents and patients prefer treatment options that are minimally invasive and that help eliminate the need for sedation.
There is no single approach that can be universally applied to all patients; Treatment time is prolonged as the treatment is carried out in stages spread over 2–3 years; Patient has a tendency to develop tongue thrust, due to creation of extraction spaces that close gradually; Extraction of posterior teeth may lead to deepening of bite
Las Vegas Raiders owner Mark Davis said he would not make any midseason decisions after being asked Wednesday about Antonio Pierce's future with the team.
The substances may act on the drug's capsule to speed up drug release, or they may stimulate the body's absorptive surfaces to increase the rate of drug uptake. Dose dumping is a disadvantage found in extended release dosage form. In general, drug companies try to avoid drugs with significant dose dumping effects. Such drugs are prone to ...
The U.S. Commerce Department said on Thursday it is considering new rules that would impose restrictions on Chinese drones that would restrict or ban them in the United States citing national ...
A black flag with white lettering lies rolled up on the ground behind the vehicle used in the New Orleans attack. The FBI said it recovered an ISIS flag, which is black with white lettering, from ...