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Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1]
The non-specific plaque hypothesis is the theory developed in the 1930s that caries is the result of the combined efforts of all the organisms in the oral biome, and that some patients are merely more susceptible than others. [8] No specific organisms had been identified at that point that were more cariogenic than others.
Osmotic release systems have a number of major advantages over other controlled-release mechanisms. They are significantly less affected by factors such as pH, food intake, GI motility, and differing intestinal environments. Using an osmotic pump to deliver drugs has additional inherent advantages regarding control over drug delivery rates.
Much less attention is paid to both the other two spheres of EBD, clinical expertise and patient values. [8]Clinical expertise plays a part in the successful outcomes of treatment with diagnostic skills preventing over and under-treatments, technical dental skills maximizing the longevity of surgical and restorative procedures and communication skills being core to patient management and ...
Clinical peer review, also known as medical peer review is the process by which health care professionals, including those in nursing and pharmacy, evaluate each other's clinical performance. [ 1 ] [ 2 ] A discipline-specific process may be referenced accordingly (e.g., physician peer review , nursing peer review ).
Compomers and glass ionomer cements can release fluoride. This property can be useful in cases where a patient has a higher risk of experience tooth decay in future. [1] [3] Fluoride is a mineral which helps strengthen our teeth and protects them from decay, and it is found in many dental products including toothpaste.
Response review For trials where the response rate is the primary endpoint it is strongly recommended that all responses be reviewed by an expert(s) independent of the study at the study's completion. Simultaneous review of the patients’ files and radiological images is the best approach. Reporting of results
Retrospective drug utilization review refers to drug therapy review that after patients have got the medication. [10] The retrospective drug utilization review has a typical process. [12] This is a computer based review. Computer will show data which are in violation of the standard.