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  2. Alcohol (drug) - Wikipedia

    en.wikipedia.org/wiki/Alcohol_(drug)

    Alcohol consumption disrupts circadian rhythms, with acute intake causing dose-dependent alterations in melatonin and cortisol levels, as well as core body temperature, which normalize the following morning, while chronic alcohol use leads to more severe and persistent disruptions that are associated with alcohol use disorders (AUD) and ...

  3. Glossary of alcohol (drug) terms - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_alcohol_(drug...

    Alcohol (from the Arabic word al-kuḥl, الكحل), sometimes referred to by the chemical name ethanol, is one of the most widely used and abused psychoactive drugs in the world. It is a central nervous system (CNS) depressant, decreasing electrical activity of neurons in the brain.

  4. Alcohol abuse - Wikipedia

    en.wikipedia.org/wiki/Alcohol_abuse

    Topiramate: Topiramate is an anticonvulsant approved for the management of epileptic seizures and used off label in the treatment of alcohol use disorder. It modulates GABA neurotransmission, and inhibits glutamate receptors, reducing cravings for alcohol and alcohol use.

  5. Treatment and management of addiction - Wikipedia

    en.wikipedia.org/wiki/Treatment_and_management...

    Because of this, treatment for alcohol addiction usually involves a combined approach dealing with dependence and addiction simultaneously. Benzodiazepines have the largest and the best evidence base in the treatment of alcohol withdrawal and are considered the gold standard of alcohol detoxification. [27]

  6. Alcoholism - Wikipedia

    en.wikipedia.org/wiki/Alcoholism

    Direct treatment can be followed by a treatment program for alcohol dependence or alcohol use disorder to attempt to reduce the risk of relapse. [9] Experiences following alcohol withdrawal, such as depressed mood and anxiety, can take weeks or months to abate while other symptoms persist longer due to persisting neuroadaptations.

  7. Disulfiram - Wikipedia

    en.wikipedia.org/wiki/Disulfiram

    Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.

  8. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    "Substance use pertains to using select substances such as alcohol, tobacco, illicit drugs, etc. that can cause dependence or harmful side effects."On the other hand, substance abuse is the use of drugs such as prescriptions, over-the-counter medications, or alcohol for purposes other than what they are intended for or using them in excessive ...

  9. Substance abuse - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse

    A study on maternal alcohol and other drug use has shown that integrated treatment programs have produced significant results, resulting in higher negative results on toxicology screens. [52] Additionally, brief school-based interventions have been found to be effective in reducing adolescent alcohol and cannabis use and abuse. [53]