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[19] [31] For drugs recently sold on the market, drugs have information pages (monographs) that provide information on any potential interaction between a medication and grapefruit juice. [19] Because there is a growing number of medications that are known to interact with citrus, [ 1 ] patients should consult a pharmacist or physician before ...
"The best way to monitor for a grapefruit medication interaction is to look out for the side effects of the drug," says Peterson "They should be listed in your paperwork from your prescription and ...
Grapefruit interaction with medication. Several medications such as statins and calcium-channel blockers shouldn’t be taken with grapefruit or its juice because of its enzyme-binding ability ...
In pharmaceutical sciences, drug interactions occur when a drug's mechanism of action is affected by the concomitant administration of substances such as foods, beverages, or other drugs. A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs .
The effect of grapefruit juice with regard to drug absorption was originally discovered in 1989. The first published report on grapefruit drug interactions was in 1991 in the Lancet entitled "Interactions of Citrus Juices with Felodipine and Nifedipine", and was the first reported food-drug interaction clinically. The effects of grapefruit last ...
Levomilnacipran has a high oral bioavailability of 92% and a low plasma protein binding of 22%. [5] [6] It is metabolized in the liver by the cytochrome P450 enzyme CYP3A4, [7] thereby making the medication susceptible to grapefruit-drug interactions.
Changing to a new medication may help you to recover from depression more effectively — or simply avoid unpleasant or persistent side effects that occurred with your previous antidepressant.
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