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Chromosome 6 spans nearly 171 million base pairs (the building material of DNA) and represents between 5.5 and 6% of the total DNA in cells. It contains the major histocompatibility complex , which contains over 100 genes related to the immune response , and plays a vital role in organ transplantation .
In humans, Chromosome 6 open reading frame 47, C6ORF47, is a single exon gene that spans 2481 nucleotides that encodes for a 294 amino acid protein. [ 5 ] [ 6 ] Location
Human chromosome 6 gene stubs (415 P) Pages in category "Genes on human chromosome 6" The following 200 pages are in this category, out of approximately 779 total.
RCCX is a complex, multiallelic, and tandem copy number variation (CNV) human DNA locus on chromosome 6p21.3, a cluster located in the major histocompatibility complex (MHC) class III region. [ 1 ] [ 2 ] CNVs are segments of DNA that vary in copy number compared to a reference genome and play a significant role in human phenotypic variation and ...
In the DNA, C6orf62 is 12,529 base pairs long and is located at 6q22.3. [7] It is located on chromosome 6 on position 22.3 (6q22.3). The mature mRNA sequence is 2498 base-pairs long with 5 exons and 4 intronic regions that translates a protein that is 229 amino acids long and two predicted isoforms of 160 amino acids and 200 amino acids.
HLA region of Chromosome 6. The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. [1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. [2]
Protein FAM46A is a protein that in humans is encoded by the FAM46A gene. Aliases for Fam46A include HBV X-Transactivated Gene 11 Protein, C6orf37, and XTP11. [5] The gene contains 6 introns, and is 6982 base pairs long. [6] The transcribed mRNA is 2231 base pairs long and contains 2 exons, 589 and 1128 base pairs, with 4 alternative splice ...
If two genes are located close together on a chromosome, the likelihood that a recombination event will separate these two genes is less than if they were farther apart. Genetic linkage describes the tendency of genes to be inherited together as a result of their location on the same chromosome.