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Multisystem inflammatory syndrome in children (MIS-C), or paediatric inflammatory multisystem syndrome (PIMS / PIMS-TS), or systemic inflammatory syndrome in COVID-19 (SISCoV), is a rare systemic illness involving persistent fever and extreme inflammation following exposure to SARS-CoV-2, the virus responsible for COVID-19. [7]
Multisystem inflammatory syndrome may refer to: . Multisystem inflammatory syndrome in children (also known as 'paediatric multisystem inflammatory syndrome', or 'paediatric inflammatory multisystem syndrome' - 'PIMS'), a rare life-threatening illness resembling Kawasaki disease that has been observed following exposure to the virus responsible for COVID-19; [1] [2] [3] while a similar ...
Some children who become infected develop a rare condition known as MIS-C, short for "multisystem inflammatory syndrome in children". [20] This causes a persistent fever and extreme inflammation. [4] [5] [13] [21] Other symptoms associated with MIS-C include severe abdominal pain and hypotension. [20] [22]
Dr. Dean Blumberg, the chief of pediatric infectious diseases with UC Davis Health, talks about the rise of MIS-C cases in California.
Post-acute infection syndromes (PAISs) or post-infectious syndromes are medical conditions characterized by symptoms attributed to a prior infection. While it is commonly assumed that people either recover or die from infections, long-term symptoms—or sequelae —are a possible outcome as well. [ 1 ]
In children, the SIRS criteria are modified in the following fashion: [11] Heart rate is greater than 2 standard deviations above normal for age in the absence of stimuli such as pain and drug administration, or unexplained persistent elevation for greater than 30 minutes to 4 hours.
Immune reconstitution inflammatory syndrome (IRIS) is a condition seen in some cases of HIV/AIDS or immunosuppression, in which the immune system begins to recover, but then responds to a previously acquired opportunistic infection with an overwhelming inflammatory response that paradoxically makes the symptoms of infection worse.
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