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Caramboxin (CBX) is a toxin found in star fruit (Averrhoa carambola) [1] [2] and the related bilimbi fruit (Averrhoa bilimbi). [3] Individuals with some types of kidney disease are susceptible to adverse neurological effects including intoxication, seizures and even death after eating star fruit [4] and bilimbi fruit. [3]
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances , both toxic chemicals and medications , on kidney function . [ 1 ] There are various forms, [ 2 ] and some drugs may affect kidney function in more than one way.
Carambola, also known as star fruit, is the fruit of Averrhoa carambola, a species of tree native to tropical Southeast Asia. [1] [2] [3] The edible fruit has distinctive ridges running down its sides (usually 5–6). [1] When cut in cross-section, it resembles a star, giving it the name of star fruit.
Lighter Side. Medicare. News. Science & Tech. Shopping. Sports. Weather. 24/7 Help. ... "Use sliced star fruit as a decorative and flavorful garnish for both sweet and savory dishes," Heckler said.
Averrhoa carambola is a species of tree in the family Oxalidaceae native to tropical Southeast Asia; [1] it has a number of common names, including carambola, star fruit and five-corner. [2] It is a small tree or shrub that grows 5 to 12 m (16 to 39 ft) tall, with rose to red-purple flowers.
A bolus intravenous dose of 10 or 20 mg of furosemide can be administered and then followed by intravenous bolus of 2 or 3% hypertonic saline to increase the serum sodium level. [ 12 ] Pulmonary edema - Slow intravenous bolus dose of 40 to 80 mg furosemide at 4 mg per minute is indicated for patients with fluid overload and pulmonary edema.
The effects of grapefruit last from 3–7 days, with the greatest effects when juice is taken an hour previous to administration of the drug. [25] In addition to grapefruit, other fruits have similar effects. Noni (Morinda citrifolia), for example, is a dietary supplement typically consumed as a juice and also inhibits CYP3A4. [26]
This review also indicates potential negative side effects on hormones and lipid levels, so that decreasing salt intake is not necessarily recommended for people with normal blood pressure. In people with chronic kidney disease, including those on dialysis, there is high-certainty evidence that dietary salt restriction may help to lower ...