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Macrolides belong to the polyketide class of natural products. Some macrolides have antibiotic or antifungal activity and are used as pharmaceutical drugs. Rapamycin is also a macrolide and was originally developed as an antifungal, but has since been used as an immunosuppressant drug and is being investigated as a potential longevity ...
Ketolide antibiotics (4 P) Pages in category "Macrolide antibiotics" The following 45 pages are in this category, out of 45 total.
The following is a list of antibiotics. ... Macrolides(Bs) Azithromycin: Zithromax, ... Drugs against mycobacteria; Clofazimine:
Carrimycin is a macrolide antibiotic.It was approved by the National Medical Products Administration of China in 2019. [1] It is approved for the treatment of acute tracheal bronchitis caused by Haemophilus influenzae, Streptococcus pneumoniae, and for the treatment of acute sinusitis caused by S. pneumoniae, H. influenzae, Streptococcus pyogenes, Moraxella catarrhalis, and Staphylococcus. [2]
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
Concomitant use with cholesterol medications such as lovastatin or simvastatin. [9] Hypersensitivity to clarithromycin or any component of the product, erythromycin, or any macrolide antibiotics. [9] QT prolongation or ventricular cardiac arrhythmias, including torsade de pointes. [9]
It is a bacterial protein synthesis inhibitor by inhibiting ribosomal translocation, [63] in a similar way to macrolides. It does so by binding to the rRNA of the bacterial 50S ribosome subunit, overlapping with the binding sites of the oxazolidinone, pleuromutilin, and macrolide antibiotics, among others. [24] [64] The binding is reversible. [65]
Some drugs can inhibit CYP3A4, which means they reduce its activity and increase the blood levels of the drugs that depend on it for elimination. This can lead to adverse effects or drug-drug interactions. [47] Azithromycin is a member of macrolides that are a class of antibiotics with a cyclic structure with a lactone ring and sugar moieties ...