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Lactucarium was used unmodified in lozenges, 30–60 milligrams (0.5 to 1 grain), sometimes mixed with borax. However, it was found to be more efficient to formulate the drug in a cough syrup (Syrupus Lactucarii, U.S.P.) containing net 5% lactucarium, 22% glycerin, 5% alcohol, and 5% orange-flower water in syrup. [6]
Lactuca quercina is a species of wild lettuce native to Europe and Asia. It is an annual or biennial herb in the tribe Cichorieae within the family Asteraceae growing from a taproot to maximum heights of 50–200 cm (19.5–78.5 in) or more.
Lactuca virosa. Lactuca virosa is a plant in the Lactuca (lettuce) genus, often ingested for its mild analgesic and sedative effects. [2] It is related to common lettuce (), and is often called wild lettuce, bitter lettuce, laitue vireuse, opium lettuce, poisonous lettuce, tall lettuce, great lettuce [3] or rakutu-karyumu-so.
Wild lettuce is a common name for several lactucarium-containing plants related to lettuce (Lactuca sativa). The name most often refers to Lactuca virosa (Europe, Asia, introduced to North America), though it may also refer to: Lactuca canadensis (North America) Lactuca ludoviciana (NW America) Lactuca serriola (Southern Europe) Lactuca ...
[10] [11] Although the standard definition of lactucarium requires its production from Lactuca virosa, it was recognized that smaller quantities of lactucarium could be produced in a similar way from Lactuca sativa and Lactuca canadensis var. elongata, and even that lettuce-opium obtained from Lactuca serriola or Lactuca quercina was of ...
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Lactucin is a bitter substance that forms a white crystalline solid and belongs to the group of sesquiterpene lactones.It is found in some varieties of lettuce and is an ingredient of lactucarium.
Lactucopicrin (Intybin) is a bitter substance that has a sedative and analgesic effect, [1] acting on the central nervous system.It is a sesquiterpene lactone, and is a component of lactucarium, derived from the plant Lactuca virosa (wild lettuce), as well as being found in some related plants such as Cichorium intybus. [2]