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The P300 wave obtained by visual stimulation is used to assess cognitive processes in humans, and the value of the latency and amplitude of the P300 wave can be a measure of the severity of dementia processes. [21] The analysis of P300 wave latency seems to be particularly useful in the diagnosis of mild cognitive impairment (MCI). [22]
In addition, there are studies on abnormalities of P300 in depression. Depressed patients tend to have a reduced P200 and P300 amplitude and a prolonged P300 latency. [20] Due to the consistency of the P300 response to novel stimuli, a brain–computer interface can be constructed which relies on it. By arranging many signals in a grid ...
The P300 response as a function of local stimulus probability. From Surprise response as a probe for compressed memory states. [1] The P300 response magnitude for both oddball and standard trials is larger the higher is the local probability of the opposite stimulus in the preceding sequence.
The P300 wave only occurs if the subject is actively engaged in the task of detecting the targets. Its amplitude varies with the improbability of the targets. Its latency varies with the difficulty of discriminating the target stimulus from the standard stimuli.
The P3a, or novelty P3, [1] is a component of time-locked signals known as event-related potentials .The P3a is a positive-going scalp-recorded brain potential that has a maximum amplitude over frontal/central electrode sites with a peak latency falling in the range of 250–280 ms.
The sweep technique is a hybrid frequency domain/time domain technique. [16] A plot of, for example, response amplitude versus the check size of a stimulus checkerboard pattern plot can be obtained in 10 seconds, far faster than when time-domain averaging is used to record an evoked potential for each of several check sizes. [16]
Specifically, latency seems to increase during tasks that are significantly complex or difficult and, thus, require greater active attention or effort. For example, the onset, peak, and offset latencies of the N1 occur significantly earlier in response to moving stimuli in a simple detection task vs. an identification task. [ 16 ]
P300 may mean: P300 (neuroscience), a neural evoked potential component of the electroencephalogram (EEG) p300 (or EP300), a transcriptional coactivator;