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The atypical antipsychotics ( AAP ), also known as second generation antipsychotics ( SGAs) and serotonin –dopamine antagonists ( SDAs ), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely ...
The difference between first- and second-generation antipsychotics is a subject of debate. The second-generation antipsychotics are generally distinguishable by the presence of 5HT2A receptor antagonism and a corresponding lower propensity for extrapyramidal side effects compared to first-generation antipsychotics. Society and culture
Typical antipsychotic. Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia ). Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions.
A big step for small. The first-generation iPhone SE (also known as iPhone SE 1 or iPhone SE 2016; SE is an initialism of Special Edition [8]) is a smartphone that was designed, developed, and marketed by Apple Inc. It is part of the 9th generation of the iPhone alongside the higher-end iPhone 6s and 6s Plus.
Clozapine is a psychiatric medication and was the first atypical antipsychotic (also called second-generation antipsychotic) to be discovered. It is primarily used to treat people with schizophrenia and schizoaffective disorder who have had an inadequate response to two other antipsychotics, or who have been unable to tolerate other drugs due to extrapyramidal side effects.
The second-generation iPhone SE (also known as the iPhone SE 2 or the iPhone SE 2020) is a smartphone designed, developed, and marketed by Apple Inc. It is part of the 13th generation of the iPhone, alongside the iPhone 11 and 11 Pro/Pro Max models. Apple announced it on April 15, 2020, coinciding with the discontinuation of the iPhone 8 and 8 ...
A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist ( DRA ), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia, bipolar disorder, and stimulant psychosis. [1]
Second-generation. Second-generation H 1-antihistamines are newer drugs that are much more selective for peripheral H 1 receptors as opposed to the central nervous system H 1 receptors and cholinergic receptors. This selectivity significantly reduces the occurrence of adverse drug reactions, such as sedation, while still providing effective ...
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