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Calcitriol is a hormone and the active form of vitamin D, normally made in the kidney. [ 8 ][ 9 ][ 10 ] It is also known as 1,25-dihydroxycholecalciferol. It binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes. [ 11 ]
Vitamin D 5. sitocalciferol. (made from 7-dehydrositosterol) Several forms (vitamers) of vitamin D exist, with the two major forms being vitamin D 2 or ergocalciferol, and vitamin D 3 or cholecalciferol. [ 1 ] The term 'vitamin D' refers to either D 2 or D 3, or both, and is known collectively as calciferol.
Vitamin D deficiency. Cholecalciferol is a form of vitamin D which is naturally synthesized in skin and functions as a pro-hormone, being converted to calcitriol. This is important for maintaining calcium levels and promoting bone health and development. [4] As a medication, cholecalciferol may be taken as a dietary supplement to prevent or to ...
Vitamin D2 vs. D3 Uses. Both vitamin D2 and vitamin D3 will help to increase vitamin D levels in the blood, says Pelitera. However, some studies have shown that supplementing vitamin D3 does a ...
Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body. [1] [7] [2] One nanogram per millilitre (1 ng/mL) is equivalent to 2.5 nanomoles per litre (2.5 nmol/L). Severe deficiency: < 12 ng/mL = < 30 nmol/L [2]
A broad reference range of 20 to 150 nmol/L (8-60 ng/mL) has also been suggested, [16] while other studies have defined levels below 80 nmol/L (32 ng/mL) as indicative of vitamin D deficiency. [ 17 ] Increasing calcifediol levels up to levels of 80 nmol/L (32 ng/mL) are associated with increasing the fraction of calcium that is absorbed from ...
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