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THC, the main psychoactive component of cannabis, may only be detectable in saliva and oral fluid for 2–24 hours in most cases. [8] [9] The main metabolite excreted in the urine is 11-Nor-9-carboxy-THC, also known as THC-COOH. Most cannabis drug tests yield a positive result when the concentration of THC-COOH in urine exceeds 50 ng/mL. [10]
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol (THC), and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Average score - positive symptoms Follow up: 12 months: On average, people receiving cannabis reduction therapy scored lower than people treated with treatment as usual but there was no clear difference between groups. This finding is based on data of moderate quality. MD 0.3 lower (2.55 lower to 1.95 higher)* Moderate Quality of life
There is a slight increase in dose proportionality in terms of peak and area-under-the-curve levels of THC with increasing oral doses over a range of 2.5 to 10 mg. [21] A high-fat meal delays time to peak concentrations of oral THC by 4 hours on average and increases area-under-the-curve exposure by 2.9-fold, but peak concentrations are not ...
Because the law limited only Δ 9-THC levels, many other cannabinoids are generally considered legal to sell and are widely available in stores and online, including Δ 8-THC, Δ 10-THC, HHC, and THCP, [68] [69] but have not had the same in-depth research that the Δ 9 isomer has on the human body; carrying potential risks in the short- or long ...
Archaeological evidence indicates cannabis with high levels of THC was being smoked at least 2,500 years ago. [1] As of 2021, cannabis is the most commonly consumed federally illegal drug in the United States, with 36.4 million people (aged 10 years or older) consuming it monthly. [2]
The average levels of THC in cannabis sold in the United States rose dramatically between the 1970s and 2000. [279] This is disputed for various reasons, and there is little consensus as to whether this is a fact or an artifact of poor testing methodologies. [ 279 ]
Medical cannabis, medicinal cannabis or medical marijuana (MMJ), refers to cannabis products and cannabinoid molecules that are prescribed by physicians for their patients. [1][2][3][4] The use of cannabis as medicine has a long history, but has not been as rigorously tested as other medicinal plants due to legal and governmental restrictions ...