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  2. List of cytochrome P450 modulators - Wikipedia

    en.wikipedia.org/wiki/List_of_cytochrome_P450...

    "INHIBITORS, INDUCERS AND SUBSTRATES OF CYTOCHROME P450 ISOZYMES". "The Life Raft Group: Long List of Inhibitors and Inducers of CYP3A4 and CYP2D6". "DRUGBANK Online: Cytochrome P-450 Enzyme Inhibitors". "MEDICATIONS METABOLIZED BY CYTOCHROME P450 3A4" (PDF)

  3. Category:Cytochrome P450 inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:Cytochrome_P450...

    Cytochrome P450 inhibitors is a category of agents that inhibit Cytochrome P450. Subcategories. This category has the following 8 subcategories, out of 8 total. A.

  4. Category:General cytochrome P450 inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:General...

    Azole cytochrome P450 inhibitors form a dative bond with the iron center. [1] Coumarin aryl-ethers, like 8-methoxypsoralen are reactive inhibitors where the compounds are de-alkylated by the P450s. ^ pubmeddev; PR, Balding; Al., Et (2020-05-06).

  5. CYP3A4 - Wikipedia

    en.wikipedia.org/wiki/CYP3A4

    Cytochrome P450 3A4 (abbreviated CYP3A4) (EC 1.14.13.97) is an important enzyme in the body, mainly found in the liver and in the intestine, which in humans is encoded by CYP3A4 gene. It oxidizes small foreign organic molecules ( xenobiotics ), such as toxins or drugs, so that they can be removed from the body.

  6. CYP1A2 - Wikipedia

    en.wikipedia.org/wiki/CYP1A2

    Following is a table of selected substrates, inducers and inhibitors of CYP1A2. Inhibitors of CYP1A2 can be classified by their potency, such as: Strong inhibitor being one that causes at least a 5-fold increase in the plasma AUC values of sensitive substrates metabolized through CYP1A2, or more than 80% decrease in clearance thereof. [18]

  7. Cytochrome P450 (individual enzymes) - Wikipedia

    en.wikipedia.org/wiki/Cytochrome_P450...

    Cytochrome P450 aromatic O-demethylase, which is made of two distinct promiscuous parts: a cytochrome P450 protein (GcoA) and three domain reductase, is significant for its ability to convert Lignin, the aromatic biopolymer common in plant cell walls, into renewable carbon chains in a catabolic set of reactions. In short, it is a facilitator of ...

  8. CYP2C9 - Wikipedia

    en.wikipedia.org/wiki/CYP2C9

    CYP2C9 is a crucial cytochrome P450 enzyme, which plays a significant role in the metabolism, by oxidation, of both xenobiotic and endogenous compounds. [7] CYP2C9 makes up about 18% of the cytochrome P450 protein in liver microsomes. The protein is mainly expressed in the liver, duodenum, and small intestine. [7]

  9. Category:CYP3A4 inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:CYP3A4_inhibitors

    Pages in category "CYP3A4 inhibitors" The following 96 pages are in this category, out of 96 total. This list may not reflect recent changes. A. Amiodarone; Amlodipine;