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  2. Biomarkers of diabetes - Wikipedia

    en.wikipedia.org/wiki/Biomarkers_of_diabetes

    In diabetic patient's, levels of the hepatocyte growth factor (HGF) were found in high levels, thus independently associated with increased the incidence of diabetes. There is a study that indicate that HGF/c-Met signalling is essential for maternal β-cell adaptation during pregnancy and that its absence/attenuation leads to gestational ...

  3. Wolfram syndrome - Wikipedia

    en.wikipedia.org/wiki/Wolfram_syndrome

    Wolfram syndrome, also called DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness), is a rare autosomal-recessive genetic disorder that causes childhood-onset diabetes mellitus, optic atrophy, and deafness as well as various other possible disorders including neurodegeneration.

  4. Diabetes insipidus - Wikipedia

    en.wikipedia.org/wiki/Diabetes_insipidus

    Diabetes insipidus (DI) is a condition characterized by large amounts of dilute urine and increased thirst. [1] The amount of urine produced can be nearly 20 liters per day. [ 1 ] Reduction of fluid has little effect on the concentration of the urine. [ 1 ]

  5. Nephrogenic diabetes insipidus - Wikipedia

    en.wikipedia.org/wiki/Nephrogenic_diabetes_insipidus

    Both cause excessive urination (hence the similarity in name), but whereas diabetes insipidus is a problem with the production of antidiuretic hormone (neurogenic diabetes insipidus) or the kidneys' response to antidiuretic hormone (nephrogenic diabetes insipidus), diabetes mellitus causes polyuria via osmotic diuresis, due to the high blood ...

  6. U.S. FDA places clinical hold on Biomea's diabetes trials

    www.aol.com/news/u-fda-places-hold-biomeas...

    The drug, BMF-219, was being tested in an early-to-mid stage study for type 2 diabetes and a mid-stage study in type 1 diabetes. The drug developer said the FDA cited deficiencies based on the ...

  7. Central diabetes insipidus - Wikipedia

    en.wikipedia.org/wiki/Central_diabetes_insipidus

    Central diabetes insipidus, recently renamed arginine vasopressin deficiency (AVP-D), [1] is a form of diabetes insipidus that is due to a lack of vasopressin (ADH) production in the brain. Vasopressin acts to increase the volume of blood (intravascularly), and decrease the volume of urine produced.

  8. US FDA says all doses of Lilly's weight-loss and diabetes ...

    www.aol.com/news/us-fda-says-doses-lillys...

    (Reuters) -All doses of Eli Lilly's weight-loss drug Zepbound and diabetes drug Mounjaro are now available, the U.S. Food and Drug Administration's updated shortage list showed on Friday. However ...

  9. Surrogate endpoint - Wikipedia

    en.wikipedia.org/wiki/Surrogate_endpoint

    The FDA and other regulatory agencies will often accept evidence from clinical trials that show a direct clinical benefit to surrogate markers. [3] Surrogate endpoints can be obtained from different modalities, such as, behavioural or cognitive scores, or biomarkers from Electroencephalography , MRI, PET, or biochemical biomarkers.