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Osteoporosis, osteomalacia and rickets are bone disorders linked to calcium metabolism disorders and effects of vitamin D. Renal osteodystrophy is a consequence of chronic kidney failure related to the calcium metabolism. A diet adequately rich in calcium may reduce calcium loss from bone with advancing (post-menopausal) age. [30]
Calcium carbonate is used in the production of calcium oxide as well as toothpaste and has seen a resurgence as a food preservative and color retainer, when used in or with products such as organic apples. [58] Calcium carbonate is used therapeutically as phosphate binder in patients on maintenance haemodialysis. It is the most common form of ...
The US Institute of Medicine (IOM) established Recommended Dietary Allowances (RDAs) for calcium in 1997 and updated those values in 2011. [6] See table. The European Food Safety Authority (EFSA) uses the term Population Reference Intake (PRIs) instead of RDAs and sets slightly different numbers: ages 4–10 800 mg, ages 11–17 1150 mg, ages 18–24 1000 mg, and >25 years 950 mg. [10]
Natural calcium is a mixture of five stable isotopes (40 Ca, 42 Ca, 43 Ca, 44 Ca, and 46 Ca) and one isotope with a half-life so long that it is for all practical purposes stable (48 Ca, with a half-life of about 4.3 × 10 19 years). Calcium is the first (lightest) element to have six naturally occurring isotopes. [14]
Hypercalciuria is the condition of elevated calcium in the urine. Chronic hypercalciuria may lead to impairment of renal function, nephrocalcinosis, and chronic kidney disease. Patients with hypercalciuria have kidneys that excrete higher levels of calcium than normal, for which there are many possible causes. Calcium may come from one of two ...
Calcium lactate has similar absorption as calcium carbonate, [42] but is more expensive. [41] [26] Unlike calcium carbonate, calcium lactate can be absorbed at various pHs, thus it does not need to be taken with food. [26] Calcium lactate is a less concentrated forms of calcium than calcium carbonate. [41] Calcium lactate contains 13% elemental ...
Calcitriol is a hormone and the active form of vitamin D, normally made in the kidney. [8] [9] [10] It is also known as 1,25-dihydroxycholecalciferol.It binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes. [11]
Careful dietary decisions should be taken since a deficient calcium intake diet accompanies the risk of excessive bone loss and can increase the absorption of dietary oxalates, found in many leafy greens and vegetables, which combine with calcium in the intestines, [29] and form oxalate kidney stones. [8]