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Tetrahydrofuran (THF), or oxolane, is an organic compound with the formula (CH 2) 4 O. The compound is classified as heterocyclic compound , specifically a cyclic ether . It is a colorless, water- miscible organic liquid with low viscosity .
Phase behavior Triple point: 164.76 K (−108.39 °C), ? Pa Critical point: 541 K (268 °C), 5190 kPa Std enthalpy change of fusion, Δ fus H o: 8.540 kJ/mol Std entropy change
Furan is a heterocyclic organic compound, consisting of a five-membered aromatic ring with four carbon atoms and one oxygen atom. Chemical compounds containing such rings are also referred to as furans.
The correlation should, however, be treated with caution. For instance, dichloromethane has a value of ε r of 9.08 (20 °C) and is rather poorly soluble in water (13 g/L or 9.8 mL/L at 20 °C); at the same time, tetrahydrofuran has its ε r = 7.52 at 22 °C, but it is completely miscible with water
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Borane–tetrahydrofuran is an adduct derived from borane and tetrahydrofuran (THF). These solutions, which are colorless, are used for reductions and hydroboration , reactions that are useful in synthesis of organic compounds .
For example, tetrahydrofuran-3-one (3-ketotetrahydrofuran) [12] and 3-aminotetrahydrofuran [13] have been synthesized from 3-hydroxytetrahydrofuran and used in pharmaceutical syntheses. Additionally, additive amounts (0.05-0.15 weight %) of the nitrate ester manufactured by sulfuric acid - nitric acid nitration of 3-hydoxytetrahydrofuran have ...
Auto-oxidation reaction is also observed with common ethers, such as diethyl ether, diisopropyl ether, tetrahydrofuran, and 1,4-dioxane. An illustrative product is diethyl ether peroxide . Such compounds can result in a serious explosion when distilled. [ 12 ]