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Stiff-person syndrome (SPS), also known as stiff-man syndrome, [1] is a rare neurological disorder of unclear cause characterized by progressive muscular rigidity and stiffness. The stiffness primarily affects the truncal muscles and is characterised by spasms , resulting in postural deformities.
Top Prescription Weight Loss Pills. Anti-obesity medications (AOMs) date back to the 1940s — well before modern regulations from the FDA (U.S. Food and Drug Administration) (FDA) were in place ...
An Ohio woman with stiff-person syndrome is opening up about her life after Celine Dion revealed she was diagnosed with the rare disorder. Skip to main content. Sign in. Mail. 24/7 Help ...
Many patients with stiff person syndrome experience muscle cramping, spasms and stiffness constantly, but certain movements or emotions can trigger "a complete, whole-body spasm," Piquet, who is a ...
High titers of autoantibodies to glutamic acid decarboxylase (GAD) are well documented in association with stiff person syndrome (SPS). [35] Glutamic acid decarboxylase is the rate-limiting enzyme in the synthesis of γ-aminobutyric acid (GABA), and impaired function of GABAergic neurons has been implicated in the pathogenesis of SPS.
Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Céline Dion is speaking out about stiff person syndrome (SPS), a diagnosis she first revealed nearly two years ago. SPS is a rare autoimmune neurological disease that affects muscles and ...
Research shows that up to 60% of the weight loss from prescription medications may come from lean body mass. Muscle loss can affect strength and mobility, so eating enough protein to preserve lean ...