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  2. Vardenafil - Wikipedia

    en.wikipedia.org/wiki/Vardenafil

    Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ...

  3. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 to 30 minutes. As with most prescription ...

  4. Things You Probably Don't Know About Viagra (Like What It Was ...

    www.aol.com/things-probably-dont-know-viagra...

    Because of the risks of this medication, people taking alpha-blockers, over-the-counter nitrate supplements (like amyl nitrate, isosorbide mononitrate, isosorbide dinitrate, or nitroglycerin) or ...

  5. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  6. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

    www.aol.com/4-common-ed-pills-weighing-141800609...

    The Best ED Medication for Men: Pros & Cons of Top ED Pills. Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world.

  7. Erectile dysfunction - Wikipedia

    en.wikipedia.org/wiki/Erectile_dysfunction

    Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity.

  8. Tips For Seniors Over 65 With ED - AOL

    www.aol.com/tips-seniors-over-65-ed-125700073.html

    Can an 80-year-old man get hard? The short answer is yes. But there are some reasons why it may be more difficult for older men to get aroused during stimulation than younger men.

  9. cGMP-specific phosphodiesterase type 5 - Wikipedia

    en.wikipedia.org/wiki/CGMP-specific_phosphodi...

    Cyclic guanosine monophosphate-specific phosphodiesterase type 5 is an enzyme (EC 3.1.4.17) from the phosphodiesterase class. It is found in various tissues, most prominently the corpus cavernosum of the clitoris and of the penis as well as the retina. [5] It has also been recently discovered to play a vital role in the cardiovascular system.

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