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Gabapentin is associated with a weight gain of 2.2 kg (4.9 lb) after 1.5 months of use. [67] Case studies indicate that it may cause anorgasmia and erectile dysfunction , [ 68 ] as well as myoclonus [ 69 ] [ 70 ] that disappear after discontinuing gabapentin or replacing it with other medication.
However, many are associated with an infamous side effect: weight gain. Luckily, some antidepressants are less likely to cause weight gain than others. In fact, there are even some antidepressants ...
Vigabatrin reduced cholecystokinin tetrapeptide-induced symptoms of panic disorder, in addition to elevated cortisol and ACTH levels, in healthy volunteers. [12]Vigabatrin is also used to treat seizures in succinic semialdehyde dehydrogenase deficiency (SSADHD), which is an inborn GABA metabolism defect that causes intellectual disability, hypotonia, seizures, speech disturbance, and ataxia ...
“There are many medications that may cause weight gain,” says W. Scott Butsch, M.D., director of obesity medicine in the Bariatric and Metabolic Institute at the Cleveland Clinic.
The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), ...
This weight gain can be driven by physical inactivity, stress, poor sleep and poor food choices, such as eating too many ultraprocessed foods, as well as medications, experts say. Weight gain by ...
Despite the fact that gabapentinoids are GABA analogues, gabapentin and pregabalin do not bind to GABA receptors, do not convert into GABA Tooltip γ-aminobutyric acid or GABA receptor agonists in vivo, and do not modulate GABA transport or metabolism. [15] [16] Conversely, GABA does not bind appreciably to the α 2 δ protein. [17]
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