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Naproxen/diphenhydramine (trade name Aleve PM) is a formulation of naproxen with diphenhydramine marketed by Bayer Healthcare. [1] It is made as an over-the-counter drug . The intended use of the drug is relieve pain specifically when going to sleep.
Naproxen's medical uses are related to its mechanism of action as an anti-inflammatory compound. [11] Naproxen is used to treat a variety of inflammatory conditions and symptoms that are due to excessive inflammation, such as pain and fever (naproxen has fever-reducing, or antipyretic, properties in addition to its anti-inflammatory activity). [11]
Most of the literature does not distinguish between PLBP and PGP as since their precise definitions often overlap, however it is possible to differentiate them through history taking, clinical examination, provocative test maneuvers, and imaging. [14] Pregnancy-related low back pain and pelvic girdle pain can occur together or separately.
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Pain following surgery can be significant, and many people require strong pain medications such as opioids. There is some low-certainty evidence that starting NSAID painkiller medications in adults early, before surgery, may help reduce post-operative pain, and also reduce the dose or quantity of opioid medications required after surgery. [29]
The majority of low back pain does not have a clear cause [1] but is believed to be the result of non-serious muscle or skeletal issues such as sprains or strains. [31] Obesity, smoking, weight gain during pregnancy, stress, poor physical condition, and poor sleeping position may also contribute to low back pain. [31]
Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative.It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects.
Pregnancy brings about significant and dynamic physiological changes that can impact sleep and contribute to sleep disorders.These changes encompass structural alterations that may affect the length and quality of sleep, disrupt breathing during sleep, and metabolic shifts that raise the risk of restless legs syndrome.