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Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).Hepatosplenomegaly can occur as the result of acute viral hepatitis, infectious mononucleosis, and histoplasmosis or it can be the sign of a serious and life-threatening lysosomal storage disease.
Portal vein thrombosis causes upper abdominal pain, possibly accompanied by nausea and an enlarged liver and/or spleen; the abdomen may be filled with fluid (). [3]A persistent fever may result from the generalized inflammation. [1]
Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...
Enlarged liver and grossly enlarged spleen (together hepatosplenomegaly) are common; [3] the spleen can rupture and cause additional complications. Skeletal weakness and bone disease may be extensive. [3] Spleen enlargement and bone marrow replacement cause anemia, thrombocytopenia, and leukopenia.
Spleen: Splenomegaly: Medical imaging: Largest dimension of over 11 cm, [27] [28] or craniocaudal height of 13 [29] cm. Moderate splenomegaly: the largest dimension is between 11–20 cm [27] Severe splenomegaly: the largest dimension is greater than 20 cm [27] Autopsy: Weight over upper limit of standard reference range, of 230 g (8.1 oz) [12 ...
These typically won’t cause pain or grow, so because I’m asymptomatic, no action is necessary. ... Liver (they can see if the liver is enlarged or it’s a fatty liver) ... Spleen. Adrenals ...
A Florida surgeon mistakenly removed a man’s liver instead of his spleen, causing him to die on the operating table, a lawyer for the man’s widow alleges. William Bryan, 70, ...
Hepatomegaly is enlargement of the liver. [4] It is a non-specific medical sign, having many causes, which can broadly be broken down into infection, hepatic tumours, and metabolic disorder. Often, hepatomegaly presents as an abdominal mass. Depending on the cause, it may sometimes present along with jaundice. [1]