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  2. Mycobacterium tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Mycobacterium_tuberculosis

    Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .

  3. Acid-fastness - Wikipedia

    en.wikipedia.org/wiki/Acid-fastness

    All Mycobacteria – M. tuberculosis, M. leprae, M. smegmatis and atypical mycobacteria. Certain Actinobacteria (especially aerobic ones in the order Mycobacteriales) with mycolic acid in their cell wall; not to be confused with Actinomyces, which is a non-acid-fast genus of actinomycete. Note that Streptomyces do not contain mycolic acid.

  4. Ziehl–Neelsen stain - Wikipedia

    en.wikipedia.org/wiki/Ziehl–Neelsen_stain

    Mycobacterium are slow-growing rod-shaped bacilli that are slightly curved or straight, and are considered to be Gram positive. Some mycobacteria are free-living saprophytes, but many are pathogens that cause disease in animals and humans. Mycobacterium bovis causes tuberculosis in cattle.

  5. Staining - Wikipedia

    en.wikipedia.org/wiki/Staining

    A Ziehl–Neelsen stain is an acid-fast stain used to stain species of Mycobacterium tuberculosis that do not stain with the standard laboratory staining procedures such as Gram staining. This stain is performed through the use of both red coloured carbol fuchsin that stains the bacteria and a counter stain such as methylene blue.

  6. Kinyoun stain - Wikipedia

    en.wikipedia.org/wiki/Kinyoun_stain

    The Kinyoun method or Kinyoun stain (cold method), developed by Joseph J. Kinyoun, is a procedure used to stain acid-fast species of the bacterial genus Mycobacterium. [1] It is a variation of a method developed by Robert Koch in 1882. Certain species of bacteria have a waxy lipid called mycolic acid, in their cell walls which allow them to be ...

  7. Tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Tuberculosis

    Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, [7] is a contagious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. [1] Tuberculosis generally affects the lungs , but it can also affect other parts of the body. [ 1 ]

  8. Mycobacterium - Wikipedia

    en.wikipedia.org/wiki/Mycobacterium

    Model of the Mycobacterium spp. cell envelope with 3-D protein structures. Mycobacteria are aerobic with 0.2-0.6 μm wide and 1.0-10 μm long rod shapes. They are generally non-motile, except for the species Mycobacterium marinum, which has been shown to be motile within macrophages. [8] Mycobacteria possess capsules and most do not form ...

  9. Niacin test - Wikipedia

    en.wikipedia.org/wiki/Niacin_test

    Redox reactions happening in Mycobacterium species produce niacin as a part of energy metabolism. Even though all mycobacteria produce niacin, M. tuberculosis accumulates an excess of niacin because of its inability to process niacin, excreting the excess niacin into the culture media, thus allowing it to be detected using the niacin test. [3]