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In general, nondisjunction can occur in any form of cell division that involves ordered distribution of chromosomal material. Higher animals have three distinct forms of such cell divisions: Meiosis I and meiosis II are specialized forms of cell division occurring during generation of gametes (eggs and sperm) for sexual reproduction, mitosis is the form of cell division used by all other cells ...
Sheffer interpreted the stroke as a sign for nondisjunction in his paper, mentioning non-conjunction only in a footnote and without a special sign for it. It was Jean Nicod who first used the stroke as a sign for non-conjunction (NAND) in a paper of 1917 and which has since become current practice.
In Boolean logic, logical NOR, [1] non-disjunction, or joint denial [1] is a truth-functional operator which produces a result that is the negation of logical or.That is, a sentence of the form (p NOR q) is true precisely when neither p nor q is true—i.e. when both p and q are false.
Nondisjunction usually occurs as the result of a weakened mitotic checkpoint, as these checkpoints tend to arrest or delay cell division until all components of the cell are ready to enter the next phase. For example, if a checkpoint is weakened, the cell may fail to 'notice' that a chromosome pair is not lined with the spindle apparatus. In ...
Nondisjunction occurs when sister chromatids on the sex chromosome, in this case an X and an X, fail to separate. An XX egg is produced, which when fertilized with a Y sperm, yields an XXY offspring. This XXY chromosome arrangement is one of the most common genetic variations from the XY karyotype, occurring in approximately one in 500 live ...
When the segregation is not normal, it is called nondisjunction. This results in the production of gametes which have either too many or too few of a particular chromosome, and is a common mechanism for trisomy or monosomy. Nondisjunction can occur in the meiosis I or meiosis II, phases of cellular reproduction, or during mitosis.
Examples of trisomies include Down syndrome (trisomy 21), Edwards syndrome (trisomy 18), and Patau syndrome (trisomy 13)." We can research any other known effects of nondisjunction and perhaps give a little more information on the molecular/cellular effects. 3. I've noticed that a lot of good articles on Wikipedia begin with a history.
Nondisjunction is when chromosomes fail to separate normally resulting in a gain or loss of chromosomes. This can happen during mitosis or meiosis. Primary nondisjunction occurs during meiosis I and the result is both members of a homologous pair go into the same daughter cell. This has the eggs have one more or one less number of chromosomes.