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In addition to the light- or H 2 O 2-induced formation of FICZ, a number of other enzymatic pathways have been identified to convert Trp to FICZ via the precursor I3A. [2] [3] Oxidative deamination of Trp by aromatic amino acid aminotransferases (ArAT) or L-amino oxidases (LAAO), one of which is the IL4-inducible enzyme IL4I1, converts Trp to indole-3-pyruvate, which after decarboxylation ...
Targeted temperature management (TTM), previously known as therapeutic hypothermia or protective hypothermia, is an active treatment that tries to achieve and maintain a specific body temperature in a person for a specific duration of time in an effort to improve health outcomes during recovery after a period of stopped blood flow to the brain. [1]
As physical work is performed, the body's natural thermoregulation (i.e. sweating) becomes ineffective. This is compounded by increased work rates, high ambient temperature and humidity levels, and direct exposure to the sun. The net effect is that desired protection from some environmental threats inadvertently increases the threat of heat stress.
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The National Academies also provide credentialed witnesses who speak before government bodies on important issues. For example, a committee chair may speak on rising mortality rates in working adults in the US to a Senate Subcommittee on Primary Health and Retirement Security, Committee on Health, Education, Labor and Pensions. [32]
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DHA is a hygroscopic white crystalline powder. It has a sweet cooling taste and a characteristic odor. It is the simplest of all ketoses and has no chiral center.The normal form is a dimer (2,5-bis(hydroxymethyl)-1,4-dioxane-2,5-diol).
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