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There are two kinds of neurons involved in the transmission of any signal through the sympathetic system: pre-ganglionic and post-ganglionic. The shorter preganglionic neurons originate in the thoracolumbar division of the spinal cord specifically at T1 to L2~L3, and travel to a ganglion, often one of the paravertebral ganglia, where they synapse with a postganglionic neuron.
This myelinated division can then enter the sympathetic chain. Here four options are available to the fibers: (1) they can run up the chain and synapse, (2) they can synapse at the level of entry, (3) they can pass straight through and synapse elsewhere – such as in the case of T5–12 (the splanchnic nerves), or (4) they can enter the chain ...
The sympathetic division emerges from the spinal cord in the thoracic and lumbar areas, terminating around L2-3. The parasympathetic division has craniosacral "outflow", meaning that the neurons begin at the cranial nerves (specifically the oculomotor nerve, facial nerve, glossopharyngeal nerve and vagus nerve) and sacral (S2-S4) spinal cord.
Another major difference between the two ANS (autonomic nervous systems) is divergence. Whereas in the parasympathetic division there is a divergence factor of roughly 1:4, in the sympathetic division there can be a divergence of up to 1:20. This is due to the number of synapses formed by the preganglionic fibers with ganglionic neurons.
The lateral grey column plays an important role in the sympathetic division of the visceral (autonomic) motor system. Neuron cell bodies in the lateral column send their axons to synapse on sympathetic ganglia that innervate autonomic and pelvic organs; in fact, all preganglionic neurons in the sympathetic nervous system originate in the ...
In the sympathetic division, neurons are mostly adrenergic (that is, epinephrine and norepinephrine function as the primary neurotransmitters). Notable exceptions to this rule include the sympathetic innervation of sweat glands and arrectores pilorum muscles where the neurotransmitter at both pre and post ganglionic synapses is acetylcholine.
The sympathetic trunk is a fundamental part of the sympathetic nervous system, and part of the autonomic nervous system. It allows nerve fibres to travel to spinal nerves that are superior and inferior to the one in which they originated. Also, a number of nerves, such as most of the splanchnic nerves, arise directly from the trunks.
Because the ANS, specifically the sympathetic division, exerts direct control over the chromaffin cells, the hormone release can occur rather quickly. [2] In response to stressors, such as exercise or imminent danger, medullary cells release the catecholamines adrenaline and noradrenaline into the blood. Adrenaline composes about 85% of the ...