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Altitude acclimatization is the process of adjusting to decreasing oxygen levels at higher elevations, in order to avoid altitude sickness. [17] Once above approximately 3,000 metres (10,000 ft) – a pressure of 70 kilopascals (0.69 atm) – most climbers and high-altitude trekkers take the "climb-high, sleep-low" approach.
CMS was first described in 1925 by Carlos Monge Medrano, a Peruvian doctor who specialised in diseases of high altitude. [3] While acute mountain sickness is experienced shortly after ascent to high altitude, chronic mountain sickness may develop only after many years of living at high altitude. In medicine, high altitude is defined as over ...
Very high altitude = 3,500–5,500 metres (11,500–18,000 ft) Extreme altitude = above 5,500 metres (18,000 ft) Travel to each of these altitude regions can lead to medical problems, from the mild symptoms of acute mountain sickness to the potentially fatal high-altitude pulmonary edema and high-altitude cerebral edema .
High-altitude pulmonary edema (HAPE) is a life-threatening form of non-cardiogenic pulmonary edema that occurs in otherwise healthy people at altitudes typically above 2,500 meters (8,200 ft). [2] HAPE is a severe presentation of altitude sickness. Cases have also been reported between 1,500–2,500 metres or 4,900–8,200 feet in people who ...
Genetic evidence suggests that the Tibetan peoples diverged from the larger Han Chinese population any time around 1,000 B.C.E. [29] [30] [31] to 7,000 B.C.E. [32] [33] Given the significant mutations to the EPAS1 gene that contribute to the Tibetan resistance to altitude sickness, this suggests that the extreme evolutionary pressure on the ...
People can become acclimatised to an altitude of 5,200 to 5,500 metres (17,000 to 18,000 ft) if they remain at high altitude for long enough, but for high altitude rescue work, rescue teams must be rapidly deployed, and the time necessary to acclimatise is not available, making oxygen breathing equipment necessary above approximately 3,700 ...
US requirements for high-altitude reconnaissance aircraft such as the U-2, and fighters to intercept high-altitude Soviet aircraft caused the US Navy to be tasked with the development of a full pressure suit in the 1950s. Working with B.F. Goodrich and Arrowhead Rubber, the USN produced a series of designs which culminated in the Goodrich Mk ...
They show a sustained increase in cerebral blood flow, lower hemoglobin concentration, and less susceptibility to chronic mountain sickness than other populations due to their longer history of high-altitude habitation. [33] [34] With the proper physical preparation, individuals can develop short-term tolerance to high-altitude conditions.