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A dendritic spine (or spine) is a small membrane protrusion from a neuron's dendrite that typically receives input from a single axon at the synapse.Dendritic spines serve as a storage site for synaptic strength and help transmit electrical signals to the neuron's cell body.
of or pertaining to the spine, the vertebra: Greek σφόνδῠλος / σπόνδυλος (sphóndulos, spóndulos), the spine spondylitis: squamos(o)-denoting something as "full of scales" or "scaly" Latin squāmōsus, full of scales, scaly squamous cell-stalsis: contraction Greek στέλλω (stéllō), I dispatch, place, set peristalsis ...
There are many recognized spinal diseases, some more common than others. Spinal disease also includes cervical spine diseases, which are diseases in the vertebrae of the neck. A lot of flexibility exists within the cervical spine and because of that, it is common for an individual to damage that area, especially over a long period of time.
The study of dendrodendritic synapses in the olfactory bulb provided some early examples of ideas about neuronal organization relating to dendritic spines [4] One spine could serve as an input-output unit; One neuron could contain multiple dendritic spines; These spines are widely spaced, indicating some independent function
Alzheimer's is a neuropathological disease that is hypothesized to result from the loss of dendritic spines and/or deformation of these spines in the patient's frontal and temporal cortices. Researchers have tied the disease to a decrease in the expression of drebrin , a protein thought to play a role in long-term potentiation , meaning the ...
The spine apparatus’ ability to release calcium into the cytosol is thought to contribute to the development of synaptic plasticity. This was first shown in an experiment using synaptopodin(SP)-deficient mice, which do not show a spine apparatus in dendritic spines. [8] These SP-deficient mice showed a decrease in long-term potentiation (LTP ...
Wallerian degeneration is an active process of degeneration that results when a nerve fiber is cut or crushed and the part of the axon distal to the injury (which in most cases is farther from the neuron's cell body) degenerates. [1]
The bases of denticulate ligaments arise in the pia mater and are firmly attached to the arachnoid mater and dura mater at the apex. [2] The denticulate ligaments extend across the subarachnoid space between anterior nerve roots and posterior nerve roots, piercing the intervening spinal arachnoid mater to reach the dura.