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A dendritic spine (or spine) is a small membrane protrusion from a neuron's dendrite that typically receives input from a single axon at the synapse.Dendritic spines serve as a storage site for synaptic strength and help transmit electrical signals to the neuron's cell body.
of or pertaining to the spine, the vertebra: Greek σφόνδῠλος / σπόνδυλος (sphóndulos, spóndulos), the spine spondylitis: squamos(o)-denoting something as "full of scales" or "scaly" Latin squāmōsus, full of scales, scaly squamous cell-stalsis: contraction Greek στέλλω (stéllō), I dispatch, place, set peristalsis ...
There are many recognized spinal diseases, some more common than others. Spinal disease also includes cervical spine diseases, which are diseases in the vertebrae of the neck. A lot of flexibility exists within the cervical spine and because of that, it is common for an individual to damage that area, especially over a long period of time.
The study of dendrodendritic synapses in the olfactory bulb provided some early examples of ideas about neuronal organization relating to dendritic spines [4] One spine could serve as an input-output unit; One neuron could contain multiple dendritic spines; These spines are widely spaced, indicating some independent function
Wallerian degeneration is an active process of degeneration that results when a nerve fiber is cut or crushed and the part of the axon distal to the injury (which in most cases is farther from the neuron's cell body) degenerates. [1]
[4] [5] Intentional denervation is a valuable surgical technique for managing some medical conditions, such as renal denervation in the setting of uncontrolled hypertension. [6] Pathological denervation, by contrast, is associated with serious health sequelae , including increased infection susceptibility and tissue dysfunction.
An apical dendrite is a dendrite that emerges from the apex of a pyramidal cell. [1] Apical dendrites are one of two primary categories of dendrites, and they distinguish the pyramidal cells from spiny stellate cells in the cortices.
Alzheimer's is a neuropathological disease that is hypothesized to result from the loss of dendritic spines and/or deformation of these spines in the patient's frontal and temporal cortices. Researchers have tied the disease to a decrease in the expression of drebrin , a protein thought to play a role in long-term potentiation , meaning the ...