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Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
Phenmetrazine has been used as an appetite suppressant for purposes of weight loss. [2] It was used therapeutically for this indication at a dosage of 25 mg two or three times per day (or 50–75 mg/day total) in adults. [2] Phenmetrazine has been found to produce similar weight loss to dextroamphetamine in people with obesity. [3]
Intentional weight loss is the loss of total body mass as a result of efforts to improve fitness and health, or to change appearance through slimming. Weight loss is the main treatment for obesity, [1] [2] [3] and there is substantial evidence this can prevent progression from prediabetes to type 2 diabetes with a 7–10% weight loss and manage cardiometabolic health for diabetic people with a ...
Due to high costs, some health plans in the US do not cover weight-loss drugs like semaglutide and tirzepatide. [ 74 ] [ 75 ] [ 76 ] In the United States, as of 2024, about half of private employer-sponsored plans cover these drugs, [ 77 ] Federal Medicare Part D does not, and only a few federally-funded, state-administered Medicaid plans do so.
Instead of the active ingredient orlistat, the counterfeit drugs contain sibutramine, and at concentrations at least twice the amount recommended for weight loss. [ 44 ] In March 2010 Health Canada advised the public that illegal "Herbal Diet Natural" had been found on the market, containing sibutramine, which is a prescription drug in Canada ...
Stanford University academic Maurice L. Tainter learned of DNP's effect in raising the metabolic rate and causing weight loss and pioneered its use as a weight loss drug. [ 1 ] [ 38 ] Although he was aware of DNP's narrow therapeutic index , Tainter tried the drugs on obese patients and published successful results in 1933; average weight loss ...
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Obesity medicine is a field of medicine dedicated to the comprehensive treatment of patients with obesity.Obesity medicine takes into account the multi-factorial etiology of obesity in which behavior, development, environment, epigenetic, genetic, nutrition, physiology, and psychosocial contributors all play a role. [1]
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