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Histopathologic types of breast cancer, with relative incidences and prognoses, with "invasive lobular carcinoma" at top right. Invasive lobular carcinoma (ILC) is breast cancer arising from the lobules of the mammary glands. [1] It accounts for 5–10% of invasive breast cancer. [2] [3] Rare cases of this carcinoma have been diagnosed in men ...
In 2003, one study found the five-year survival rate of invasive carcinoma NST was approximately 85%. [29] In general, greater tumor size and presence of lymph node metastasis predicts higher risk of recurrence after initial diagnosis and treatment.
The overall 5-year survival rate for both invasive ductal carcinoma and invasive lobular carcinoma was approximately 85% in 2003. [9] Ductal carcinoma in situ, on the other hand, is in itself harmless, although if untreated approximately 60% of these low-grade DCIS lesions will become invasive over the course of 40 years in follow-up.
The overall 5-year survival rate of lobular carcinoma in situ has been estimated to be 97%. [16] LCIS (lobular neoplasia is considered pre-cancerous) is an indicator (marker) identifying women with an increased risk of developing invasive breast cancer. This risk extends more than 20 years.
Lobular carcinoma is a form of tumor which primarily affects the lobules of a gland. It is sometimes considered equivalent to "terminal duct carcinoma". [1] If not otherwise specified, it generally refers to breast cancer. Examples include: Lobular carcinoma in situ; Invasive lobular carcinoma
The most common cancer among women in the United States is breast cancer (123.7 per 100,000), followed by lung cancer (51.5 per 100,000) and colorectal cancer (33.6 per 100,000), but lung cancer surpasses breast cancer as the leading cause of cancer death among women. [13]
SPC is considered invasive when the tumor nests have a characteristic jigsaw growth pattern with ragged and irregular margins with the loss of myoepithelial cells at the site(s) of invasion. [21] Rarely, invasive SPC occurs with nearby invasive carcinoma of NST, lobular carcinoma, cribriform carcinoma, or tubular carcinoma breast tumors. [3]
Compared to infiltrating ductal carcinomas, medullary breast carcinoma has a better prognosis and a significantly higher survival rate. The best measure of prognosis is through staging and axillary lymph node involvement in the absence of metastatic disease. The higher the involvement of lymph nodes, the worse the prognosis. [9] There is also ...