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  2. Is Sildenafil Safe for This Common Male Problem? - AOL

    www.aol.com/sildenafil-safe-common-male-problem...

    Sildenafil is most commonly prescribed to be taken one time per day in doses between 25 and 100 mg for ED. Your healthcare provider will determine the best dosage for you based on a number of factors.

  3. How to Take Viagra for Best Results - AOL

    www.aol.com/viagra-best-results-105700318.html

    According to the Food and Drug Administration (FDA), it usually takes 30 to 60 minutes for Viagra or generic sildenafil to start producing a noticeable improvement in your climax quality.

  4. Do You Know What Viagra Was Originally Used For? (Plus What ...

    www.aol.com/viagra-treats-side-effects-plus...

    Studies have shown a 70 to 80 percent success rate in patients who use this treatment. ... Sildenafil can still be used to treat hypertension, but today, the primary use of this PDE5 inhibitor is ...

  5. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil. Thus, the metabolite is responsible for about 20% of sildenafil's action. Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and to a lesser extent in the urine (around 13% of the administered oral dose).

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  7. What Happens If You Take Viagra and You Don't Need It? - AOL

    www.aol.com/happens-viagra-dont-105800158.html

    In many of these studies, the researchers found more than 10 percent of men having intimacy with men used sildenafil citrate — and that its use is associated with higher risks of unprotected ...

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