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Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
Subsequently, the National Academy of Sciences (NAS) reviewed the health implications of perchlorate, and in 2005 proposed a much higher alternative reference dose of 0.0007 mg/kg/day based primarily on a 2002 study by Greer et al. [6] During that study, 37 adult human subjects were split into four exposure groups exposed to 0.007 (7 subjects ...
For the drugs administered by oral and dermal route, the units of threshold dose are mg/kg body-weight/day (dose of the drug in mg per body weight in kg per day) or ppm (parts per million), while the threshold dose of drugs by inhalation delivery has the unit of mg/L 6h/day (amount of drug in mg in 1L of air, for 6 hours per day). [8]
A Duke University animal study funded by the Sugar Association [25] found evidence that doses of Splenda (containing ~1% sucralose and ~99% maltodextrin by weight) between 100 and 1000 mg/kg BW/day, containing sucralose at 1.1 to 11 mg/kg BW/day, fed to rats reduced gut microbiota, increased the pH level in the intestines, contributed to ...
English Possible confusion aa, āā, ĀĀ ana of each AAA apply to affected area abdominal aortic aneurysm: a.c. ante cibum: before meals a.c.h.s., ac&hs ante cibum et hora somni: before meals and at bedtime a.d. auris dextra: right ear a single-storey a can be mistaken as an o which could read "o.d.", meaning right eye ad., add. adde addatur: add
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The result is expressed in mg/kg body mass. Dermal Toxicity : LD 50 for acute dermal toxicity means that dose of the material which, administered by continuous contact for 24 hours with the shaved intact skin (avoiding abrading) of an albino rabbit, causes death within 14 days in half of the animals tested.