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  2. 7-Methylxanthine - Wikipedia

    en.wikipedia.org/wiki/7-methylxanthine

    7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine). [1] [2] It is a non-selective antagonist of the adenosine receptors. [1] [2] The compound may slow the progression of myopia (nearsightedness). [1] [2] It is under investigation for this ...

  3. Caffeine - Wikipedia

    en.wikipedia.org/wiki/Caffeine

    1,3,7-Trimethyluric acid is a minor caffeine metabolite. [5] 7-Methylxanthine is also a metabolite of caffeine. [193] [194] Each of the above metabolites is further metabolized and then excreted in the urine. Caffeine can accumulate in individuals with severe liver disease, increasing its half-life. [195]

  4. Methylxanthines - Wikipedia

    en.wikipedia.org/wiki/Methylxanthine

    Download as PDF; Printable version; In other projects ... Caffeine (1,3,7-trimethylxanthine) General references. Fredholm, Bertil B. (22 September 2010).

  5. 1,3,7-Trimethyluric acid - Wikipedia

    en.wikipedia.org/wiki/1,3,7-Trimethyluric_acid

    1,3,7-Trimethyluric acid, also referred to as trimethyluric acid and 8-oxy-caffeine, is a purine alkaloid that is produced in some plants and occurs as a minor metabolite of caffeine in humans. [1] The enzymes that metabolize caffeine into 1,3,7-trimethyluric acid in humans include CYP1A2 , CYP2E1 , CYP2C8 , CYP2C9 , and CYP3A4 .

  6. Theophylline - Wikipedia

    en.wikipedia.org/wiki/Theophylline

    Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. [1] It is used to treat chronic obstructive pulmonary disease (COPD) and asthma. [2] Its pharmacology is similar to other methylxanthine drugs (e.g., theobromine and caffeine). [1]

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