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In advanced lipodermatosclerosis the proximal leg swells from chronic venous obstruction and the lower leg shrinks from chronic ulceration and fat necrosis resulting in the inverted coke bottle appearance of the lower leg. [7] Lipodermatosclerosis is most commonly diagnosed in middle-aged women. [3]
Chondroid lipomas are deep-seated, firm, yellow tumors that characteristically occur on the legs of women. [7]: 625 Corpus callosum lipoma is a rare congenital brain condition that may or may not present with symptoms. [11]
A Baker's cyst, also known as a popliteal cyst, is a type of fluid collection behind the knee. [4] Often there are no symptoms. [2] If symptoms do occur these may include swelling and pain behind the knee, or knee stiffness. [1] If the cyst breaks open, pain may significantly increase with swelling of the calf. [1]
A noticeable lump in relation to an extremity may be the first presenting symptom. Multiple deformities can arise, namely coronal plane deformities around the knees, ankles, shoulders, elbows, and wrists. For example, genu valgum (knock knees), ankle valgus, ulnar bowing and shortening, and radial head subluxation are encountered.
The first signs of dracunculiasis occur around a year after infection, as the full-grown female worm prepares to leave the infected person's body. [2] As the worm migrates to its exit site – typically the lower leg – some people have allergic reactions, including hives, fever, dizziness, nausea, vomiting, and diarrhea. [6]
Lipedema is a condition that is almost exclusively found in women [3] and results in enlargement of both legs due to deposits of fat under the skin. [2] Women of any weight may be affected [2] [3] and the fat is resistant to traditional weight-loss methods. [4]
Milroy's disease (MD) is a familial disease characterized by lymphedema, commonly in the legs, caused by congenital abnormalities in the lymphatic system. Disruption of the normal drainage of lymph leads to fluid accumulation and hypertrophy of soft tissues.
[10] [17] The fat deposited around the front of the neck is known as Madelung's collar or horse collar. [13] [5] Fat deposited on the back of the neck between the shoulder blades is known as a dorsocervical fat pad or buffalo hump. [13] [18] Fat deposited in the parotid region is known as hamster cheeks. [10]